Amberen® contains proprietary ingredients that are manufactured using our own patent-pending “smart molecule” technology.
Lunada Biomedical is the only company in the world that has a manufacturing facility capable of producing these unique ingredients.
We are the only company in the world that has the technology to produce “smart molecules” of succinates and fumarates (key ingredients in Amberen) with specific shapes that are bio-identical to those produced in the human body. This means our compounds are shaped for optimal performance.
The succinate anion is derived from Ammonium Succinate and, in this form, penetrates any biological membranes at the fastest rate. Once ingested, it functions as a signaling molecule and metabolic substrate. The principal signaling action involves the activation of the sympathetic function of the central and peripheral nervous systems, which results in increased sensitivity and normalized function of the hypothalamus. This activation effectively regulates the entire endocrine system. In addition, succinates contribute to the stabilization of Hypoxia Inducible Factor (HIF), which accounts for improvement of the blood flow and the, speeding-up of the synthesis of erythrocytes, is responsible for transporting oxygen, and aids in the adaptation of the metabolism to hypoxic conditions. In other words, the body better adjusts to oxygen deficiency induced by cardiovascular pathologies or during strenuous physical activities. Ammonium Succinate is an energy metabolism substrate, combined with ammonium ions, and it stabilizes mitochondrial activity in the cells. Mitochondria are the “energy stations” of each cell, especially active in the cells of the heart, liver and kidneys. An interesting point to note is that while succinates contribute to mitochondrion stimulation under the condition of energy and oxygen deficiency, they have an opposite effect in the event of mitochondrial hyperactivity. Mitochondrial hyperactivity provokes the production of active forms of oxygen and nitrogen, also known as free radicals.
In this case, Ammonium Succinate slows down mitochondrial activity and suppresses the generation of free radicals at the mitochondrial level, acting like a specific, water-soluble antioxidant. Therefore, succinates in the body possess energy-regulating, hypoxi-preventing and adaptogenic properties on both the regulatory and metabolic level, which can help the body cope with physical or psycho-emotional stress.
Calcium Disuccinate is the source of an easily absorbed calcium, which is vital for regulating myocardial contractility and formation of the bone tissue.
Monosodium L-Glutamate is a salt of an amino acid, and functions as a neurotransmitter. It also regulates the chemical reactions of transamination.
We use safe, small amount (40mg per each dose of Amberen) of pharmaceutical-grade bioactive Monosodium L-Glutamate, which is very different from the quality and quantity of MSG used in processed foods.
Studies show that Monosodium L-Glutamate isn’t likely to cause an allergic reaction, or any other adverse side effects, unless you use extremely high doses (1,000 ‒ 10,000 times higher than recommended). To the contrary, small dosages of Monosodium L-Glutamate, as used in Amberen, have been shown to positively affect the performance of mitochondrial-benzodiazepine receptors in peripheral tissues and stabilize energy status.
A more detailed explanation is available on FDA website:
Glycine is an amino acid, involved in the processes regulating brain cell activity. In combination with magnesium, it lowers the sensitivity of glutamate receptors and makes brain mitochondria more resistant to hypoxia, which, in turn, results in the normalization of the psycho-emotional balance in the body.
Magnesium Disuccinate Hydrate
Magnesium Disuccinate Hydrate is the source of an easily absorbed magnesium, which is essential for a healthy cardiovascular system. It is also vital for the effective engaging and regulation of ATP in all energy-dependent cell reactions and for the synthesis of ferments, containing magnesium. Furthermore, it performs the functions of regulation and inhibition of the central and peripheral glutamate receptors.
Zinc Difumarate Hydrate
Zinc Difumarate Hydrate is one of the sources of zinc and fumarate, which play an important role in energy metabolism. Zinc ions are essential for the formation of ferments with active zinc centers, which are involved in important processes of synthesis occurring in the body. Sufficient amounts of zinc enhance the metabolism of beta cells in the pancreatic islets of Langerhans and promote insulin synthesis and deposition. This in turn contributes to the normalization of fat and carbohydrate metabolism.
Vitamin E (in its form as Tocopherol Acetate) is a fat-soluble, natural antioxidant that prevents lipid peroxidation of cell membranes. Cell organelles and most importantly, the DNA contained in the nucleus, rely on the cell membrane to protect them. Antioxidant properties of tocopherol, supplemented by water-soluble succinate anions, promote the stabilization of membrane structure, as well as generic cell functions.
Amberen Inactive Ingredients: Gelatin, Rice Flour, Magnesium Stearate, Silicon Dioxide, Titanium Dioxide, Riboflavin, Carmin, Water.
Amberen Weight Loss IngredientsAmberen Weight Loss
Amberen Weight Loss contains Propolmannan, a highly effective solution that will help you reduce body weight by promoting a feeling of fullness.Propolmannan
(Amorphophallus konjac K. Koch, ssp. Amorphophallus japonica) fiber extract (root)Vegan capsule